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Clinical research on pyridoxine in relation to neurological effects (see Table 2 for particular person/anecdotal proof) Duration Dosage Authors Subjects Number of Findings Conclusions (mg/day) treatment Adverse Too few topics to Baker and Elderly 6 225 up to 1 yr results not provide useful knowledge; Frank (1984) reported full data not revealed All topics developed abnormal Clear evidence of measurements opposed results at Berger et al Adults 5 one thousand-3000 as much as 7 of vibration excessive doses with an (1992) months and/or thermal inverse relationship thresholds; four between dose and topics devesymptom-free duration loped scientific symptoms Diabetic No adjustments in Limited period Bernstein and sufferers with up to 6 motor conducand high drop-out fee 16 150 Lobitz (1988) pre-current months tion velocity at (solely 5 subjects studied neuropathies 5 months at 5 months) Shooting efficiency (a refiection of tremor); Duration too Bonke and Men 18 60 (n = 8) eight weeks important short to evaluate Nickel (1989) (marksmen) 600 (n = 10) improvement in neurological effects score over the eight week period in comparison with placebo No neurological Only 7% of sufferers Patients with results have been handled for Brush (1988) premenstrual cohort 1 forty-200 principally much less reported three or extra years. 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