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Dr Muir has an Efudix season stretching from late April via to the end of October - the treatment is a lot better tolerated in these cooler months - he explains to his sufferers that it takes some years to develop solar keratoses so a number of months wont matter Dr Muir uses a variety of regimes - each dermatologist he has ever spoken to about this topic has their very own regime - typical approaches include the following: (i) With a stoical affected person, especially one who has used efudix before, Dr Muir will use it twice a day to all the skin of the face - he will evaluate at two weeks - relying on the degree of irritation seen he'll then determine how long to keep going - often they're very inflamed at two weeks and he will cease then - typically he'll maintain going for the complete three weeks and rarely, if there is little response, 4 weeks or extra (ii) Dr Muir tells the affected person to use the cream to all the affected skin not simply the seen keratoses - that way they will pick up clinical and sub-clinical lesions - if they're involved by the level of irritation, they can scale back the frequency of software or stop altogether and call me - we are able to at all times recommence in spite of everything (iii) With a nervous patient or one with lots of photo voltaic keratoses Dr Muir will use pulse remedy - that is where one applies efudix twice a day two days per week - the opposite five days are remedy free days - if they get too infected they can apply some topical steroid ointment on the non-efudix days - they need to apply the efudix on these days when they are going to be getting the least quantity of solar For occasion: - in the event that they play cricket on Sunday he will get them to use it on Monday and Tuesday thereby minimizing the amount of inflammation when they are outdoor - ideally of course they might avoid sun publicity altogether Dr Muir will keep this up for 6-16 weeks relying on how they go - he warns them that the clearance rate with this might be lower then with the usual b. 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