Prophylactic Management of Human or Animal Bite Wounds to Prevent Infection Category of Management Management Cleansing Remove visible dirt Cleanse the wound surface with cleaning soap and water, saline, 1% povidone�iodine, or 1% benzalkonium chloride Irrigate with a copious volume of sterile saline answer by high-stress syringe irrigationa Do not irrigate puncture wounds; Standard Precautions ought to be used Wound tradition No for recent wounds, except indicators of infection exist Yes for wounds that seem infectedb Diagnostic imaging Indicated for penetrating injuries overlying bones or joints, for suspected fracture, or to assess international body inoculation Debridement Remove superfcial devitalized tissue Operative debridement Yes if any of the next: and exploration � Extensive wounds (devitalized tissue) � Involvement of the metacarpophalangeal joint (clenched fst harm) � Cranial bites by large animal Wound closure Yes for selected contemporary, nonpuncture chunk wounds (see text) Assess tetanus immunization Yes statusc Assess risk of rabies from animal Yes bitesd Assess danger of hepatitis B virus Yes infection from human bitese Assess risk of human immunodefYes ciency virus from human bitesf Initiate antimicrobial therapyg Yes for: � Moderate or severe chunk wounds, particularly if edema or crush injury is current � Puncture wounds, particularly if penetration of bone, tendon sheath, or joint has occurred � Facial chunk wounds � Hand and foot bite wounds � Genital area chunk wounds � Wounds in immunocompromised and asplenic folks � Wounds with indicators of an infection Follow-up Inspect wound for signs of infection inside forty eight h aUse of an 18-gauge needle with a large-volume syringe is efficient. 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